Blar i Bergen Open Research Archive på forfatter "Lu, Yu"

Viser treff 1-4 av 4

    • Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension 

      White, Kevin; Lu, Yu; Annis, Sofia; Hale, Andrew E.; Chau, B. Nelson; Dahlman, James E.; Hemann, Craig; Opotowsky, Alexander R.; Vargas, Sara O.; Rosas, Ivan; Perrella, Mark A.; Osorio, Juan C.; Haley, Kathleen J.; Graham, Brian B.; Kumar, Rahul; Saggar, Rajan; Saggar, Rajeev; Wallace, W. Dean; Ross, David J.; Khan, Omar F.; Bader, Andrew; Gochuico, Bernadette R.; Matar, Majed; Polach, Kevin; Johannessen, Nicolai; Prosser, Haydn M.; Anderson, Daniel G.; Langer, Robert; Zweier, Jay L.; Bindoff, Laurence; Systrom, David; Waxman, Aaron B.; Jin, Richard C.; Chan, Stephen Y. (Peer reviewed; Journal article, 2015)
      Iron–sulfur (Fe‐S) clusters are essential for mitochondrial metabolism, but their regulation in pulmonary hypertension (PH) remains enigmatic. We demonstrate that alterations of the miR‐210‐ISCU1/2 axis cause Fe‐S deficiencies ...

    • Low Molecular Weight Hydrogel for Wound Healing 

      Gu, Shangyan; Lu, Yu; Wang, Yuji; Lu, Wensheng; Wang, Wei (Journal article; Peer reviewed, 2023)
      Octadecylazanediyl dipropionic acid (C18ADPA) is a zwitterionic amphiphile with a dendritic headgroup. C18ADPA self-assembles to lamellar networks, which encompasses water and forms a low-molecular-weight hydrogel (LMWG). ...

    • An NMR Study on Hydration and Molecular Interaction of Phytantriol‐Based Liquid Crystals 

      Lu, Yu; Zhu, Di; Le, Quynh Bao Truong; Wang, Yuji; Wang, Wei (Journal article; Peer reviewed, 2022-10-27)
      Phytantriol-based lyotropic liquid crystals (LLCs) have emerged as a new nanodrug delivery system. However, the understanding of phytantriol-based LLCs is lacking. In this study, we use NMR technology to characterize LLC ...

    • Ruthenium-based antitumor drugs and delivery systems from monotherapy to combination therapy 

      Lu, Yu; Zhu, Di; Le, Quynh Bao Truong; Wang, Yuji; Wang, Wei (Journal article; Peer reviewed, 2022)
      Ruthenium complex is an important compound group for antitumor drug research and development. NAMI-A, KP1019, TLD1433 and other ruthenium complexes have entered clinical research. In recent years, the research on ruthenium ...